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CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed)

US · MD · Bethesda National Institutes of Health (NIH) grant open #PAR-25-077
Response due Oct 16, 2026 · 00:00 UTC

Summary

The National Institutes of Health (NIH) is soliciting basic research grant applications (R01 mechanism) under the CounterACT (Countermeasures Against Chemical Threats) program, specifically focused on chemical threats that affect the nervous system. This is part of the Chemical Countermeasures Research Program (CCRP) Initiative. Clinical trials are explicitly excluded from this funding opportunity. The goal is to advance foundational scientific understanding of neurological chemical threats and develop potential countermeasures.

What they want

Applicants must conduct basic research related to chemical threats that affect the nervous system under the NIH CounterACT program. The work falls under the CCRP (Chemical Countermeasures Research Program) Initiative. Clinical trials are not allowed under this funding opportunity announcement (FOA number PAR-25-077). Research must align with the R01 grant mechanism, which supports investigator-initiated, independent research projects.
Technical requirements
  • Basic (non-clinical) research only — clinical trials explicitly not allowed
  • Must use R01 grant mechanism
  • Research must focus on chemical threats affecting the nervous system
  • Must align with NIH CounterACT program objectives

Risks & flags

  • No dollar values or award sizes disclosed in the notice, limiting competitive intelligence
  • Long open window (nearly 2 years) may indicate rolling/multiple submission cycles rather than a single competition

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541711
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

CCRP Initiative: NIH Countermeasures Again…
Due Oct 16
Onboard ↗