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Evaluating the Impact of Non-Invasive Brain Stimulation on Learning and Consolidation of Phonologically Similar Novel Spoken Words

US · IL National Institutes of Health grant awarded #nih-5R21HD108576-02

Summary

This project aims to use repetitive transcranial magnetic stimulation (rTMS) to investigate the neural mechanisms underlying word learning difficulties in older youth with and without reading disabilities, specifically focusing on phonologically similar novel spoken words.

What they want

The study will employ a within-subjects design with two groups of participants (20 typically developing youth and 20 older youth with reading difficulties, aged 16-21). Participants will complete visual phonological discrimination tasks, spoken artificial lexicon learning, and novel word retention tasks following either active or sham rTMS applied to a dorsal stream node of the reading network. Exploratory analyses will also evaluate associations between baseline neural activation variability (measured during a functional magnetic resonance imaging task) and individual differences in the magnitude of modulatory effects observed.
Technical requirements
  • Repetitive transcranial magnetic stimulation (rTMS)
  • Functional magnetic resonance imaging (fMRI)
  • Visual phonological discrimination tasks
  • Spoken artificial lexicon learning tasks
  • Novel word retention tasks

Market context

inferred from NAICS
R&D in Physical, Engineering, Life Sciences (except Nanotech & Biotech)
NAICS 541715
US market size
$95B
Typical award
$100K – $50M+
Typical buyers
DoDNSFNIHNASADOE
Commonly required
DCAA-compliant accountingITARCMMC L2
Evaluating the Impact of Non-Invasive Brai…
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