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Horizontal gene transfer as the source of evolutionary innovation in eukaryotes

US National Institute of General Medical Sciences grant open #nih-5R01GM111917-12

Summary

PROJECT SUMMARY Horizontal gene transfer (HGT) represents a dominant force in bacterial evolution, however its role in shaping the evolutionary processes in eukaryotic genomes has been a subject of intense debate. Class Bdelloidea of the phylum Rotifera, a large invertebrate taxon comprising close to 500 described species, has so far withstood any challenges questioning the massive amounts of HGT from non-metazoan sources reported in their genomes, and remain the record-holders among Metazoa with regard to the proportion of foreign genes, with HGT candidates comprising at least 8% of all codin

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