Summary
ABSTRACT: Cocaine use disorder (CocUD) imposes significant medical, economic, and psychosocial burdens globally. Here we propose to explore the potential efficacy and safety of psilocybin, a serotonergic hallucinogenic compound found in psychedelic mushrooms, as a possible treatment for addiction to cocaine, which is a form of stimulant use disorder, but which we refer to herein as CocUD. Psychedelics are being explored as a novel therapy for mood, anxiety, and addictive disorders due to their ability to induce acute perceptual changes (i.e., a psychedelic effect). Studies suggest psychedelics
