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NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)

US National Institutes of Health (NIH) grant open #PAR-25-052
Response due Nov 19, 2026 · 00:00 UTC

Summary

The National Institutes of Health (NIH) is soliciting applications under the StrokeNet program for clinical trials and biomarker studies focused on stroke treatment, recovery, and prevention. The opportunity uses the UG3/UH3 phased cooperative agreement mechanism, with clinical trials listed as optional. The program aims to advance research through the established NIH StrokeNet infrastructure. The funding opportunity is open for an extended two-year window from November 2024 through November 2026.

What they want

Technical requirements
  • Must align with NIH StrokeNet network infrastructure
  • Clinical trials are optional under the UG3/UH3 phased cooperative agreement mechanism
  • Biomarker study components must relate to stroke treatment, recovery, or prevention

How they evaluate

Submission: Grants.gov federal grants portal (electronic submission)

Risks & flags

  • Ultra-long response window (2 years) is typical for NIH Program Announcement with Review (PAR) mechanisms and is not itself a red flag, but narrow alignment to StrokeNet infrastructure may favor applicants already embedded in the StrokeNet network
  • UG3/UH3 phased mechanism requires milestone-driven phase transition, which can disadvantage applicants without prior StrokeNet affiliation

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541711
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

NIH StrokeNet Clinical Trials and Biomarke…
Due Nov 19
Onboard