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Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R01 Clinical Trial Optional)

US · MD National Institutes of Health (NIH) grant open #PAR-25-290
Response due Jan 07, 2028 · 00:00 UTC

Summary

This NIH funding opportunity (PAR-25-290) solicits R01 research grant applications leveraging invasive neural recording and stimulation procedures in human subjects to advance scientific understanding of neural circuitry underlying mental health disorders. The opportunity is open to clinical trial research as an optional component. It is posted under the National Institutes of Health (HHS) and targets neuroscience and mental health research communities. The opportunity window spans over three years, from late 2024 through early 2028.

What they want

Technical requirements
  • Research must utilize invasive neural recording and/or stimulating procedures in human subjects
  • Clinical trial inclusion is optional
  • Must focus on neural circuitry mechanisms related to mental health disorders

How they evaluate

Submission: Grants.gov federal grants portal (electronic submission)

Risks & flags

  • Highly specialized scope (invasive human neural recording/stimulation) narrows the eligible applicant pool significantly to a small number of research institutions with neurosurgical and neuromodulation capabilities

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541711
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

Utilizing Invasive Recording and Stimulati…
Due Jan 07
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