Summary
Project Summary Pain is a complex phenomenon that elicits somatosensory and motor reflexive responses together with marked and long-lasting changes in emotional and autonomic states. While acute pain provides protection from tissue damage, chronic or long-lasting pain, provides no protective function and is often incapacitating. Chronic pain conditions are debilitating to patients, their families, and society by reducing quality of life and creating enormous financial consequences that total more than 630 billion USD annually for the United States of America alone. Neuropathic pain is a type o