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Establishing a Center for the Advancement of Substance Use Disorder (SUD) Pharmacotherapeutics through Training and Preclinical Support (U54 Clinical Trial Not Allowed)

US · MD · Bethesda National Institutes of Health (NIH) / National Institute on Drug Abuse (NIDA) grant unknown #RFA-DA-27-015

Summary

The National Institutes of Health (NIH), via the National Institute on Drug Abuse (NIDA), is forecasting a funding opportunity to establish a research center focused on advancing pharmacotherapeutics for Substance Use Disorders (SUD). The center will emphasize researcher training and preclinical support activities. Clinical trials are explicitly excluded from this award mechanism. This is a U54 Research Center cooperative agreement funding opportunity announced under RFA-DA-27-015.

What they want

Establish a center dedicated to advancing SUD pharmacotherapeutics through two core activities: (1) researcher training programs and (2) preclinical research support. The award mechanism is a U54 Research Center cooperative agreement. Clinical trials are not allowed under this opportunity (RFA-DA-27-015). The center is expected to build infrastructure, capacity, and expertise in the development of new pharmacological treatments for substance use disorders at the preclinical stage.
Technical requirements
  • Clinical trials are NOT allowed under this funding opportunity
  • Must establish a center structure consistent with NIH U54 Research Center cooperative agreement requirements
  • Must include preclinical research support components
  • Must include researcher training programs

How they evaluate

Submission: Grants.gov federal grants portal submission (standard NIH application process expected upon full publication)

Risks & flags

  • Opportunity is currently in 'forecasted' status — full requirements, eligibility, and evaluation criteria are not yet published
  • U54 cooperative agreements of this nature often favor large academic medical centers or established research institutions with existing SUD/pharmacology infrastructure, which may disadvantage newer entrants

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541712
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

Establishing a Center for the Advancement …
$unknown
Onboard