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Effect of WASH interventions on population resilience to seasonally-driven enteric pathogen transmission along a gradient of socio-economic position

US · IL NIH grant awarded #nih-5R03AI188012-02

Summary

This study aims to measure the effect of integrated Water, Sanitation, and Handwashing (WASH) interventions on seasonally-driven enteric pathogen seroconversion among rural Bangladeshi children, examining how these effects vary along a gradient of socio-economic position.

What they want

The project will utilize serology data for 10 enteric pathogens collected from a birth cohort of 3,831 children (and a substudy of ~1,500 children) from an ongoing cluster-randomized trial. Researchers will measure the effect of WASH interventions on enteric pathogen seroconversion based on monsoon season exposure and socio-economic position using generalized additive models. Geospatial methods will be employed to transport pathogen-specific effects from the trial to broader populations in rural Bangladesh to identify vulnerable regions.
Technical requirements
  • Serology of 10 enteric pathogens
  • Generalized additive models
  • Geospatial methods
Effect of WASH interventions on population…
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