Summary
The Advanced Mass Spectrometry Facility provides support for principal investigator (PI) projects, primarily from NIDDK, focusing on biopolymer analysis, small molecule chemistry, and proteomics, alongside methodology updates and development.
What they want
The facility supports approximately 40 PIs and 70 annual projects, with significant involvement in small molecule chemistry and biopolymer analysis for NIDDK. It also updates and adopts new methodologies, and in limited cases, develops new approaches when immediately important to ongoing PI projects. Proteomics projects, especially proximity ligation type experiments using isotope-based quantitative approaches, are a key focus. Efforts are also made to improve work efficiency and method development on a low-cost liquid handler.
Deliverables
- Support for PI projects
- Biopolymer analysis
- Small molecule analysis
- Proteomics data
- Updated methodologies
- Developed new analytical approaches
Technical requirements
- Advanced Mass Spectrometry
- Proteomics
- Isotope-based quantitative approach
- Liquid handler
Key personnel
- Single staff member (for proteomics)
- Deputy Chief of the LDB (acting as gatekeeper for projects)