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Ancillary Studies to Ongoing Clinical Projects (RP1 Clinical Trial Not Allowed)

US · IL National Institutes of Health (NIH) grant open #PAR-27-049

Summary

This is a National Institutes of Health (NIH) funding opportunity (PAR-27-049) for ancillary studies attached to ongoing clinical projects. The mechanism explicitly excludes clinical trials (RP1 Clinical Trial Not Allowed), meaning proposed research must be observational or non-interventional in nature. The opportunity is currently in a forecasted status, opening June 12, 2025. As a federal grant posted on Grants.gov, it supports investigator-initiated ancillary research piggy-backed onto existing clinical infrastructure.

What they want

Applicants must propose ancillary studies — secondary research activities conducted in conjunction with already-ongoing clinical projects. Clinical trials are explicitly not allowed under the RP1 activity code. Work must leverage existing clinical study infrastructure. Full programmatic requirements, eligibility criteria, and application instructions are contained in the complete funding opportunity announcement (FOA) PAR-27-049 on Grants.gov/NIH.
Technical requirements
  • Proposed studies must be ancillary to an already-ongoing clinical project
  • Clinical trials are explicitly prohibited under this mechanism (RP1 Clinical Trial Not Allowed)
  • Research must conform to NIH RP1 activity code requirements

How they evaluate

Submission: Grants.gov federal grants portal (electronic submission)

Risks & flags

  • Opportunity is in 'forecasted' status — full requirements, deadlines, and evaluation criteria are not yet published, limiting advance preparation time once fully released.
  • No response due date, budget ceiling, or period of performance disclosed in the forecast notice — bidders/applicants cannot size or plan efforts.

Market context

inferred from NAICS
Professional, Scientific & Technical Services
NAICS 541711
US market size
$2.0T
Typical award
$25K – $50M
Typical buyers
All federal civilianDoDStates
Commonly required
8(a)WOSBSDVOSBPE/PMP

Sector-level estimate — full code lookup not yet in catalog.

Ancillary Studies to Ongoing Clinical Proj…
$unknown
Onboard ↗