Summary
Negative social experiences are a main driver of HIV disparities among Latino men who have sex with men (LMSM), negatively affecting non-injection substance use (e.g. methamphetamine) and PrEP uptake. Addressing factors that influence PrEP cascade progression, such as negative social experiences and methamphetamine use, are essential to ending the HIV epidemic. Negative social experiences can occur across various sources (i.e. family, friends, others), mechanisms (i.e. anticipated, enacted), and types, which compound to produce and exacerbate deleterious health outcomes among LMSM. Social netw