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Showing 25 / 21760 · page 10/871
Tobacco Mosaic Virus as a mucosal delivery platform for an intranasal vaccine against Pseudomonas aeruginosa
US · IL NIH · grant
Pseudomonas aeruginosa (PA) is a gram-negative opportunistic pathogen that is one of the most prominent causes of healthcare acquired infections worldwide. It is also a significant cause of morbidity and mortality associated with burn wound…
Posted May 21, 2026
Promoting Change in Practice for Respiratory Failure: the PRECIPICE Study
US · IL NIH RePORTER (National Heart, Lung, and Blood Institute - NHLBI) · grant
PROJECT SUMMARY Background: Approximately 300,000 Hispanic individuals experience respiratory failure each year in the U.S. Hispanic patients are twice as likely to die from respiratory failure as non-Hispanic patients. There is an urgent n…
Posted May 21, 2026
Defining mechanisms of action of Menin inhibition in AML
US · IL NIH · grant
Abstract Project 3 Acute myeloid leukemia (AML), and specifically KMT2A-rearranged (KMT2A-r) and NPM1 mutant AML, remain devasting disease with an overall poor prognosis for high risk pediatric and adult patients. AML is characterized by ab…
Posted May 21, 2026
Defining epigenetic mechanisms in NPM1c mutant leukemia
US · IL National Institutes of Health · grant
Project Summary/Abstract Nucleophosmin (NPM1) mutations are among the most common aberrations in acute myeloid leukemia (AML) and cause a characteristic stem cell-like gene expression pattern including the upregulation of HOXA/B cluster gen…
Posted May 21, 2026
1Florida Alzheimer's Disease Research Center Clinical Core
US National Institute on Aging · grant
The goal of the 1Florida ADRC is to advance the understanding of Alzheimer’s disease and Related Disorders (ADRDs), especially in underrepresented minority groups. Among 370 participants currently recruited at Mount Sinai Medical Center (…
Posted May 21, 2026
Cancer Control and Survivorship Program
US National Cancer Institute · grant
PROJECT SUMMARY/ABSTRACT—Cancer Control and Survivorship Program The overarching goal of the Cancer Control and Survivorship Program (CCSP) is to conduct highly innovative clinical, genetic, and observational research, and translate our f…
Posted May 21, 2026
Mach-LETSGO: Machine-LEarning of Treatment, Survey, and Genetics towards Obtaining Correct Classification of Chronic Conditions in Adult Survivors in the Childhood Cancer Survivor Study - CCSS Suppl
US · IL NIH · grant
ABSTRACT Mach-LETSGO leverages machine learning to improve the accuracy of chronic health condition classification in the Childhood Cancer Survivor Study (CCSS; U24 CA055727; PI: Armstrong), addressing limitations of its self- reported data…
Posted May 21, 2026
Childhood Cancer Survivorship Study
US · IL NIH · grant
ABSTRACT The Childhood Cancer Survivor Study (CCSS) is a multi-institutional, multi-disciplinary collaborative research resource established to systematically evaluate long-term outcomes among children diagnosed with cancer who survived fiv…
Posted May 21, 2026
Lung interstitial macrophage remodeling during and after recovery from pneumococcal respiratory infection
US National Heart Lung and Blood Institute · grant
Project Summary Worldwide, acute lower respiratory tract infections, including pneumococcal pneumonia, are a major cause of mortality among all infectious diseases. Streptococcus pneumoniae continues to be the leading cause of bacterial pne…
Posted May 21, 2026
C-type natriuretic peptide in hypertrophic cardiomyopathy
US National Heart Lung and Blood Institute · grant
PROJECT SUMMARY/ABSTRACT The overall objective of this proposal is to further our understanding of the biology and therapeutic potential of C-type natriuretic peptide in hypertrophic cardiomyopathy (HCM). Cardiac fibrosis a key risk factor …
Posted May 21, 2026
Improving the science of adherence reinforcement and safe mobility in people with diabetic foot ulcers using smart offloading
US · IL National Institutes of Health (NIH) · grant
PROJECT SUMMARY/ABSTRACT We aim to reduce the limb-threatening and life-limiting burden of neuropathic diabetic foot ulcers (DFU) by advancing science in its most critical component: protective pressure offloading. We intend to do this via…
Posted May 21, 2026
Using Open-Source Technology to Measure Energy Expenditure and Sleep Among Children 3 to 8 Years Old
US National Heart Lung and Blood Institute · grant
Assessing children’s 24-hour movement behaviors (i.e., time spent active, sedentary, and asleep) can reveal the complex and interdependent ways energy expenditure and sleep are related to health outcomes. However, assessing energy expenditu…
Posted May 21, 2026
Causes and Consequences of Preschooler's Digital Media Use: The Role of Sleep, Physical Activity, Sedentary Behavior and Social Emotional Health
US Eunice Kennedy Shriver National Institute of Child Health and Human Development · grant
Excessive screen time for children ages 3-5 years is linked with poor sleep, inactivity, and behavior problems. The WHO recommends children under 5 get <1 hour of screen time per day, but few children meet this guideline. This is partly att…
Posted May 21, 2026
Causes and Consequences of Preschooler's Digital Media Use: The Role of Sleep, Physical Activity, Sedentary Behavior and Social Emotional Health
US · IL National Institutes of Health (NIH) · NAICS 541715 · $unknown · grant
Excessive screen time for children ages 3-5 years is linked with poor sleep, inactivity, and behavior problems. The WHO recommends children under 5 get <1 hour of screen time per day, but few children meet this guideline. This is partly att…
Posted May 21, 2026
Light Microscopy Digital Imaging
US National Cancer Institute · grant
Abstract Light Microcopy & Digital Imaging (LMDI-SR) Light microscopy and digital imaging is integral to COHCCC’s research mission. The LMDI-SR provides a wide range of instruments that allow investigators to image numerous sample types in …
Posted May 21, 2026
Assessment of Treatment Satisfaction in Psoriasis
US · IL NIH · grant
PROJECT SUMMARY / ABSTRACT Treatments for plaque psoriasis vary substantially in effectiveness and side effects. It is often difficult to determine the optimal treatment during a patient-centric, shared decision-making process between the c…
Posted May 21, 2026
Spatialomics and quantitative MRI of ischemic injury in a piglet model of Legg-Calve-Perthes disease
US · MN NIH RePORTER · grant
PROJECT SUMMARY This K01 award will provide training and protected research time for Alexandra Armstrong, DVM, DACVP, PhD to achieve her career goal of becoming an independently-funded investigator with specialty expertise in animal models …
Posted May 21, 2026
Peptide Nucleic Acid (PNA) Oligomers for Targeted Disruption of Biomolecular Condensates in ALS/FTD
US National Institute of Neurological Disorders and Stroke · grant
PROJECT SUMMARY The formation of biomolecular condensates (BMCs) is an important phenomenon in biology, creating transient compartments that can accelerate biochemical reactions or sequester molecules during times of stress. Aberrations in …
Posted May 21, 2026
Elucidating a novel respiratory-mammary axis of T cell immunity
US National Institute of Allergy and Infectious Diseases · grant
Breastfeeding is associated with immunological benefits that persist beyond infancy, including reduced risk of respiratory infection. While these benefits are often attributed to immunoglobulins and antimicrobial compounds, human milk is al…
Posted May 21, 2026
Outreach & Engagement Core
US · IL NIH · grant
Cancer is the second leading cause of mortality for Native Americans.1 In Arizona (AZ), only the Navajo Nation and the Hopi Tribe have Centers for Disease Control and Prevention funding through the National Breast and Cervical Cancer Early …
Posted May 21, 2026
Defining the role of lncRNA Neat1 and the nuclear paraspeckle in regulating macrophage innate immune gene expresison
US · IL NIH · grant
PROJECT SUMMARY To ensure a robust immune response to pathogens without risking immunopathology, the kinetics and amplitude of inflammatory gene expression in macrophages need to be exquisitely well-controlled. To mount balanced inflammator…
Posted May 21, 2026
Ecological Assessment of Proximal Risk Factors for Suicide During Care Transitions
US · IL NIH · NAICS 541720 · grant
Project Summary/Abstract Suicidal ideation and behavior are growing public health problems in the United States. This is particularly concerning during the high-risk period following discharge from psychiatric hospitalization when risk for …
Posted May 21, 2026
A Prospective, Longitudinal Investigation of Physical Activity and Bone Health among Female Adolescents Recovering from Restrictive Eating Disorders
US · IL NIH · grant
PROJECT SUMMARY/ABSTRACT Restrictive eating disorders (EDs) most commonly affect female adolescents and can lead to low bone mineral density (BMD) and impaired bone microarchitecture. Peak bone accrual occurs during adolescence, and the pr…
Posted May 21, 2026
Hands-on Science Education for Future Leaders in Biomedical and Behavioral Research
US National Institute on Drug Abuse · grant
The mission of this SEPA grant at California State University San Marcos (CSUSM) is to foster future scholars of science by engaging motivated youth and their families in a structured, comprehensive science education, mentoring, and researc…
Posted May 21, 2026
Novel Methods for Joint Prediction in the presence of mortality
US National Heart Lung and Blood Institute · grant
Project Summary and Abstract Health care decisions are made in challenging clinical settings where patients and physicians have to con- tend with complex trade-offs across a range of longitudinal and time-to-event quality-of-life outcomes …
Posted May 21, 2026