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Showing 25 / 21760 · page 48/871
Immune System Development and Regulation
US National Institute of Allergy and Infectious Diseases · grant
This program requests the continuation of 4 predoctoral positions for training in immune system development and regulation (ISDR). The program includes 26 faculty trainers with expertise in the development and regulation of the immune syste…
Posted May 21, 2026
Purinergic Receptors in Myeloma
US · IL NIH · grant
Project summary The purpose of this project is to identify novel regulators of ER homeostasis in malignant plasma cells that can be targeted to induce the death of these cells and/or prevent upstream events that foster plasma cell malignanc…
Posted May 21, 2026
Biochemical Mechanisms for Sustained Humoral Immunity
US · IL NIH · grant
Project summary Antibody-secreting plasma cells play critical roles in health and disease, yet little is known about the biochemical mechanisms controlling antibody synthesis and secretion or how these pathways intersect with pathways contr…
Posted May 21, 2026
Proteasome Targeting for Alloreactive Plasma Cells
US · IL NIH · grant
Abstract The induction of plasma cells that secrete antibodies against donor tissue alloantigens is a major barrier to successful transplantation. Moreover, because many plasma cells are remarkably long-lived, the resulting antibody titers …
Posted May 21, 2026
Language is Medicine: A Caregiver-Implemented Language Intervention to Prevent Developmental Delay in Dine Toddlers
US National Institute on Minority Health and Health Disparities · grant
PROJECT SUMMARY/ABSTRACT Native American (NA) toddlers and preschoolers experience a high rate of preventable developmental delay (DD) which contributes to decreased kindergarten readiness and often results in the need for special education…
Posted May 21, 2026
UCSD Integrated Cardiovascular Epidemiology Fellowship
US National Heart Lung and Blood Institute · grant
SUMMARY/ABSTRACT The objective of the T32 funded “Integrated Fellowship on the Epidemiology and Prevention of Cardiovascular Disease" is to rigorously train physicians and behavioral scientists in epidemiologic and behavioral research meth…
Posted May 21, 2026
Optimized Strategies to Support Implementation of Remote Patient Monitoring for Diabetes Management in High-Risk Pregnancy: A Feasibility Study
US National Institute of General Medical Sciences · grant
RESEARCH PROJECT 2: PROJECT SUMMARY/ABSTRACT Women residing in rural areas of the United States (U.S.) face higher maternal health risks, including a 9% increased likelihood of severe maternal morbidity and mortality compared to their urb…
Posted May 21, 2026
Colorado Nurse Family Heart Trial for the ENRICH program
US National Heart Lung and Blood Institute · grant
PROJECT SUMMARY Cardiovascular disease (CVD) is the leading cause of death in the United States, with disparately greater impact on racial/ethnic minorities and lower-income individuals. Risk for CVD begins very early in life as adverse exp…
Posted May 21, 2026
Auditory-perceptual motor speech features in preschoolers: Norms and utility in differentiating childhood apraxia of speech and dysarthria
US · IL NIH · grant
PROJECT SUMMARY Childhood apraxia of speech (CAS) and dysarthria are two neurological motor speech disorders that can have long-term negative effects on communication and participation for 1-2/1000 children in the general population and up …
Posted May 21, 2026
04 Immunology
US · IL National Cancer Institute (NCI) · $5M-25M · grant
PROJECT SUMMARY/ABSTRACT The Immunology Program includes 30 members (26 primary, 3 associate, 1 adjunct) from 9 departments. The program is led by Dr. James Allison, an international authority on exploring fundamental mechanisms of the immu…
Posted May 21, 2026
Comparative Data Analytics Core
US National Institute on Aging · grant
Project Summary (Comparative Data Analytics Core) Researching aging biology presents unique methodological challenges. To maximize the impact of aging research, it is essential to have a wide range of statistical expertise within and suppor…
Posted May 21, 2026
Stargardt/ABCA4 disease in African Americans
US · IL NIH · grant
Project summary/Abstract Disease-associated variation in the ABCA4 gene has emerged as the most prevalent cause of Mendelian retinal disease affecting an estimated 50,000 people in the United States. The extensive clinical heterogeneity of …
Posted May 21, 2026
Development of a Novel Therapeutic for Melioidosis
US · IL NIH · grant
To support the advanced development of candidate therapeutics for biodefense pathogens or emerging infectious diseases. The supported research and development activities will progress the therapeutic product development and may include lead…
Posted May 21, 2026
Research Project 1 - Allerton
US · IL NIH · grant
Project Summary Heart failure with preserved ejection fraction (HFpEF) will soon become the predominant form of heart failure. Patients with cardiometabolic HFpEF have multiple co-morbidities including obesity, hypertension, and diabetes. T…
Posted May 21, 2026
Viral Testing Core
US · IL NIH · grant
PROJECT SUMMARY/ABSTRACT – VIRAL TESTING CORE Continuous, accurate surveillance for agents of concern is an essential requirement for maintenance of a specific pathogen-free (SPF) breeding colony. In 2009, we transitioned from testing at of…
Posted May 21, 2026
Exercise for Memory Rehabilitation in Epilepsy
US · IL NIH · grant
Project Summary/Abstract Approximately 50% of the 3.4 million persons with epilepsy (PWE) in the U.S. have cognitive problems with memory deficits reported most commonly. Memory deficits negatively contribute to the personal and profession…
Posted May 21, 2026
Veterinary Medicine Research Branch
US · IL National Institute of Mental Health (NIMH), National Institutes of Health (NIH) · grant
The NIMH Veterinary Medicine Research Branch (VMRB) has successfully provided veterinary medical, husbandry and research support to over twenty-four (24) principal investigators in the NIMH IRP, with over forty-seven (47) active animal stud…
Posted May 21, 2026
Veterinary Research and Resources Section
US National Eye Institute · grant
The NEI Veterinary Research and Resources Section (VRRS) has successfully provided support to veterinary medical, husbandry and research support to the NEI ACUC and approximately twenty-two (22) principal investigators in the NEI DIR with s…
Posted May 21, 2026
Posttranslational regulation of macropinocytosis in pancreatic cancer
US · IL NIH · grant
The majority of pancreatic ductal adenocarcinoma (PDAC) patients present with late-stage, metastatic disease that is often resistant to therapeutics, resulting in the lowest survival rate of all major cancers. Metabolic rewiring in response…
Posted May 21, 2026
Interactive Outbreak Simulator: A Robust and Customizable Platform for Socio-Epidemiological Insights
US · IL NIH · grant
Project Summary / Abstract The long-term objectives of this work are to develop a platform for modeling disease transmission during outbreaks, and to deploy that platform into research laboratories and public health settings across the Unit…
Posted May 21, 2026
Impact of Developmental Glutamatergic Signaling on Oligodendrocyte Differentiation
US National Institute of Neurological Disorders and Stroke · grant
Project Oligodendrocytes nervous propagation. involves proliferation development. developing chemogenetically preliminary precursor development of also maturation. early Here elucidate glutamate Summary (OLs) produce myelin, a lipid rich me…
Posted May 21, 2026
Large-scale Implementation of Community Co-led Maternal Sepsis Care Practices to Reduce Morbidity and Mortality from Maternal Infection
US Eunice Kennedy Shriver National Institute of Child Health and Human Development · grant
In the United States, infection is now the most common cause of direct maternal mortality and the third leading cause overall after cardiovascular conditions and other pre-existing medical conditions. Nationally, there has been no improveme…
Posted May 21, 2026
Iron Based Coupling Media (IBCM) for MRI-guided Transcranial Ultrasound Surgeries
US National Institute of Biomedical Imaging and Bioengineering · grant
Project Summary/Abstract Fatal or impairing neurological diseases, including movement disorders, brain cancers, psychological disorders, epilepsies, malformations, and memory disorders, impose heavy burdens on both individuals and society a…
Posted May 21, 2026
Mixed methods research to increase engagement and smoking abstinence among African Americans enrolled in Quitline text messaging services
US National Institute on Drug Abuse · grant
Cigarettes are used by over 34 million U.S. adults and cause more than 480,000 deaths annually due to smoking and smoke exposure. Despite smoking at similar rates and consuming less cigarettes per day, African Americans are more likely to d…
Posted May 21, 2026
Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children
US Eunice Kennedy Shriver National Institute of Child Health and Human Development · grant
Project Summary/Abstract Postpartum smoking relapse rates have remained stagnant for over a decade with more than 50% of those who are able to achieve smoking abstinence during pregnancy relapsing within the first few months after childbirt…
Posted May 21, 2026