91 grants

PROJECT SUMMARY/ABSTRACT Inflammation is the body's response to tissue damage, including brain tissue after stroke. Stroke is one of the leading causes of death and disability, affecting more that 79

Abstract: The corpus callosum – the largest fiber tract in the human brain, connects and integrates the two cerebral hemispheres. Agenesis of the corpus callosum (ACC) with an incidence of 1 in 2,000

PROJECT SUMMARY RELEVANCE: Approximately 1 in 4 U.S. adults suffers from multimorbidity, or two or more concurrent chronic diseases. People with multimorbidity experience more disability and higher mo

PROJECT SUMMARY Cerebral Palsy (CP) is a common lifelong neurological disorder affecting movement and posture, requiring ongoing physical therapy to achieve functional gains. This project aims to eval

Abstract Many people with aphasia (PwA) lose contact with the majority of their friends in the months following the onset of this disorder. Losing friendships and the ensuing social isolation place a

PROJECT SUMMARY/ABSTRACT Disease Modifying Agents (DMAs) are vital for reducing inflammation and limiting disease activity in multiple sclerosis (MS). However, there is a decline in inflammation and d

The Clinical Research Core (RC1) is a key resource for the University of Florida (UF) Older Americans Independence Center (OAIC), providing the resources and expertise for conducting research across t

The Clinical Research Core (RC1) is a key resource for the University of Florida (UF) Older Americans Independence Center (OAIC), providing the resources and expertise for conducting research across t

Although new treatments have improved outcomes in rheumatoid arthritis (RA), disability remains high, most patients have ongoing disease activity, and lasting remissions are rare. A major gap in the f

Rheumatoid arthritis (RA) affects approximately 1% of the population and is characterized by inflammation and joint damage, often leading to considerable disability and pain in both early and establis

Rheumatoid arthritis (RA) affects approximately 1% of the population and is characterized by inflammation and joint damage, often leading to considerable disability and pain in both early and establis

Rheumatoid arthritis (RA) affects approximately 1% of the population and is characterized by inflammation and joint damage, often leading to considerable disability and pain in both early and establis

Although new treatments have improved outcomes in rheumatoid arthritis (RA), disability remains high, most patients have ongoing disease activity, and lasting remissions are rare. A major gap in the f

PROJECT SUMMARY: Deficits in cognitive control are core features of late-life depression, contributing both to emotion dysregulation and problems with inhibiting irrelevant information, conflict detec

PROJECT SUMMARY Anti-3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) immune mediated necrotizing myopathy (IMNM) is an increasingly recognized, severe subset of autoimmune myopathy that causes signi

PROJECT SUMMARY Alzheimer’s disease is a leading cause of functional disability among older adults worldwide. Despite the inevitability of functional impairment in Alzheimer’s disease, large heterogen

PROJECT SUMMARY Alzheimer’s disease is a leading cause of functional disability among older adults worldwide. Despite the inevitability of functional impairment in Alzheimer’s disease, large heterogen

PROJECT SUMMARY Femoroacetabular impingement syndrome (FAIS) is a common cause of hip pain and disability and a known risk factor for hip osteoarthritis (OA). Patients with FAIS present with a loss o

PROJECT SUMMARY Infections with the parasitic nematode Ascaris lumbricoides affect up to an estimated 1.2 billion people worldwide, causing significant disease and accounting for the loss of 749,000

Project Summary Pediatric patients are more vulnerable to radiation exposure when compared to adults. Each year, 2.2 million pediatric head computed tomography (CT) scans utilizing ionizing radiation

PROJECT ABSTRACT Our goal for the DS-CHANGE Training Program is to build data science capacity at Kwame Nkrumah University of Science and Technology (KNUST) and develop a cadre of qualified data scien

Abstract This application proposes to address priority areas for improvement in the care of multiple sclerosis (MS) in Colombia (a low-middle income country), which is a country with a population tha

ABSTRACT The prevalence of autism and attention-deficit/hyperactivity disorder (ADHD) is increasing, yet their etiology is poorly understood. A complex combination of environmental and genetic factors

Project Abstract Poor environmental conditions such as air pollution, and unsafe water and sanitation have been ranked among the top risk factors for disability-adjusted years (DALYs) in children. The

Adolescence is a complex time of heightened self-consciousness, risk taking and peer orientation which may be especially challenging for teens diagnosed with autism spectrum disorder (ASD). Longitudin