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Showing 25 / 21760 · page 17/871
Cell Cycle Control Of Arterial-Venous Specification Within the Developing Embryo
US · IL NIH · grant
Project Summary: The blood vascular circulatory system is composed of arterial, venous, and capillary vessels, which work together to facilitate the efficient exchange of gasses, nutrients, and waste from all tissues, while regulating bloo…
Posted May 21, 2026
NMDOH Scientific Laboratory Division Retail Meat Surveillance Program
US Food and Drug Administration · grant
Project Summary Antimicrobial resistance is one of our most serious health threats. Antimicrobial use in food animals can lead to antibiotic-resistant infections in humans. Infections from resistant bacteria are now too common, and some pat…
Posted May 21, 2026
Population genomics in peripartum cardiomyopathy
US · IL NIH · NAICS 541714 · grant
PROJECT SUMMARY Peripartum cardiomyopathy (PPCM) is a form of heart failure characterized by left ventricular dysfunction that occurs during late pregnancy or shortly after delivery. This condition causes a sudden weakening of the heart mu…
Posted May 21, 2026
Population Assessments of Aggregate Genetic Risk for Dilated Cardiomyopathy
US National Heart Lung and Blood Institute · grant
PROJECT SUMMARY Candidate. Krishna G. Aragam, MD MS is a board-certified physician in internal medicine and cardiology at Massachusetts General Hospital (MGH), an Instructor in Medicine at Harvard Medical School (HMS), and an affiliated res…
Posted May 21, 2026
Structural and Functional Studies of Cell-Adhesion Receptors
US · IL NIH · grant
Project Abstract Cellular communication is essential for the development of all multicellular organisms, and is a key phenomenon that is disrupted in many human diseases. Cell-surface receptors mediate cellular communication and are the tar…
Posted May 21, 2026
Integrated Therapies for Alcohol use in Alcohol-associated Liver Disease (ITAALD) - Virginia Commonwealth University
US · VA National Institutes of Health · grant
Severe alcohol-associated hepatitis (sAH) has high short-term mortality, yet it currently has no FDA-approved therapy. Although return to drinking impacts quality of life and mortality in these patients, available pharmacological treatments…
Posted May 21, 2026
Cardiometabolic Health and Epigenetic Aging Across the Life Course Among Hispanic/Latino Immigrant Groups in the United States
US · IL NIH · grant
PROJECT SUMMARY (ABSTRACT) Hispanic/Latino populations in the United States (U.S.) carry a disproportionate burden of poor cardiometabolic health outcomes, with higher rates of obesity, diabetes, and hypercholesterolemia than non-Hispanic W…
Posted May 21, 2026
Kansas Center for Metabolism and Obesity REsearch (KC-MORE) - Cells, Tissues, Bioanalysis and Biostatistics Core
US National Institute of General Medical Sciences · grant
CELLS, TISSUES, BIOANALYSIS AND BIOSTATISTICS CORE: PROJECT SUMMARY Adding a translational component to confirm ideas generated using in vitro and animal models is a vital part of biomedical research. This is especially critical for a multi…
Posted May 21, 2026
Degradomics of proteolytic mechanisms in post-traumatic osteoarthritis
US · IL NIH · grant
Osteoarthritis (OA) is usually diagnosed when joint damage is well under way. Its early detection and treatment continue to be elusive, requiring greater knowledge of pathogenic processes and potential drug targets active early in the disea…
Posted May 21, 2026
Investigating the regulation of T cell-mediated autoimmunity in type 1 diabetes by microRNA146a
US National Institute of Diabetes and Digestive and Kidney Diseases · grant
PROJECT SUMMARY/ABSTRACT Type 1 diabetes (T1D) is a chronic autoimmune disease that results in destruction of pancreatic islet beta cells by autoreactive T lymphocytes. T1D is the most common form of diabetes in children less than 15 years …
Posted May 21, 2026
Novel Over-the-Scope Platform for Control of Variceal Bleeding
US · IL NIH · grant
Abstract Upper gastrointestinal (UGI) bleeding from variceal hemorrhage marks a major turning point in the life of a patient with cirrhosis. Up to 20% of these patients will die from the event. A major shortcoming in the treatment of UGI va…
Posted May 21, 2026
How NTS NPY neurons alter NTS circuitry to promote food intake
US · IL NIH · grant
Obesity is a major health problem in the United States and a leading contributor to cardiovascular disease, diabetes mellitus and stroke. One region essential for the control of meal size is the nucleus of the solitary tract (NTS) in the br…
Posted May 21, 2026
The Enteric Glia as a Possible Target for Symptom Relief in Endometriosis
US · IL NIH · grant
Endometriosis, a chronic painful gynecological disorder defined as the presence of endometrial glands and stroma outside the endometrial cavity, is characterized by peritoneal inflammation, fibrosis, adhesions, and ovarian cysts. Women with…
Posted May 21, 2026
Research Education Core
US National Cancer Institute · grant
The Research Education Core (REC) of the Ponce Health Sciences University and Moffitt Cancer Center Partnership has built an educational program that supports participants across the career continuum, preparing them for basic or clinical …
Posted May 21, 2026
Molecular Mechanisms of Non-muscle Myosin II Contractility
US · IL NIH RePORTER · grant
PROJECT SUMMARY/ABSTRACT Non-muscle myosin II (NMII) contractility is critical to number cellular processes from development to disease. NMII is an ATP-dependent molecular motor that functions as a dimer composed of two heavy chains, which …
Posted May 21, 2026
PEG Hydrogels to Investigate the Role of Vasa Vasorum Angiogenesis in Tissue Engineered Vascular Grafts
US National Heart Lung and Blood Institute · grant
PROJECT SUMMARY Tissue engineered vascular grafts (TEVGs) are a promising alternative to autologous tissues, yet none have been clinically approved for small-diameter revascularization due to pathological remodeling. Our lab previously sho…
Posted May 21, 2026
Tracing the Impact of Evolving Environmental Exposure to Tobacco, Cannabis, and Nicotine Smoke and Vapor Emissions on Children's Mental Health Symptom Trajectories
US · IL NIH · grant
PROJECT SUMMARY Background: In recent years, while combustible cigarette smoking has decreased, use and co-use of electronic nicotine delivery systems (ENDS) and cannabis smoking has increased among adults of reproductive age. This suggests…
Posted May 21, 2026
Embrace Genomics
US · IL National Institutes of Health (NIH) · NAICS 611430, 611710 · grant
Genetics and genomics have become increasingly important in research and medicine. The understanding of the genetic contribution to disease is quickly expanding from rare disease to common disease, making genetics and genomics relevant to a…
Posted May 21, 2026
New low cost technology for early detection of ear disorders
US · IL NIH · NAICS 339112, 541715 · grant
Most conductive hearing loss stems from pathologies affecting the tympanic membrane (TM), including perforations, retraction pockets, cholesteatoma, atelectasis, and tympanosclerosis. These conditions often go undetected until significant h…
Posted May 21, 2026
Development of a high performance reduced cost OCT Otoscope
US · IL NIH · NAICS 339112 · grant
The method physicians use to examine the tympanic membrane (TM) and middle ear (ME) in clinical settings has remained largely unchanged for the past 150 years. Typically, a speculum is inserted into the ear canal, with the physician using a…
Posted May 21, 2026
Role of glucagon-like peptide-1 signaling in mediating sensory-specific satiety
US · IL NIH · NAICS 541715 · grant
PROJECT SUMMARY/ABSTRACT Despite its critical role in meal cessation, the neuroendocrine mechanisms underlying sensory-specific satiety (SSS) are largely unknown. SSS is the transient reduction in motivation and pleasantness for a recently…
Posted May 21, 2026
Liquid biopsy approaches to inform neuroblastoma prognosis and disease monitoring
US · IL NIH · NAICS 541714 · grant
Abstract Fewer than half of all children with high-risk neuroblastoma become long-term survivors. Currently, it is not possible to predict if a child will be cured with standard therapy or is destined to relapse. Furthermore, standard clini…
Posted May 21, 2026
Meaning-Centered Psychotherapy to Meet Palliative Care Needs of Cancer Caregivers
US National Cancer Institute · grant
PROJECT SUMMARY In 2020, 53 million people in the U.S. served as family caregivers, the partners, relatives, and friends who provide assistance (i.e., physical, emotional) to patients with often life-threatening, incurable illnesses. Caregi…
Posted May 21, 2026
TASK ORDER 1 - OCR PROJECT MANAGEMENT, DSMB AND CROMS-RELATED SUPPORT
US · IL NIH RePORTER · grant
Alzheimer's disease
Posted May 21, 2026
Tumor Suppressor Protein, p53
US · IL NIH · grant
The p53 tumor suppressor protein is a key component of the cellular response to stress. It is a homo-tetrameric, sequence-specific transcription factor activated by DNA damage, hypoxia, heat shock, and other types of stress and regulates DN…
Posted May 21, 2026