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21,760 contracts

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Showing 25 / 21760 · page 29/871
Neuromuscular electrical stimulation for physical function maintenance during hematopoietic stem cell transplantation
US · IL NIH RePORTER · NAICS 541715 · grant
Hematopoietic cell transplantation (HCT) reduces physical function and muscle mass and increases fatigue. Neuromuscular electrical stimulation (NMES), when used as a stand-alone intervention, improves muscle strength and muscle mass in non-…
Posted May 21, 2026
Seattle Summer Research Program in Geriatrics and Disparities
US Veterans Affairs · grant
We are applying to renew the “Seattle Summer Research Program in Geriatrics and Disparities” at the VA Puget Sound Health Care System (VAPSHCS), Seattle, WA. The VAPSHCS ranks 4th in research funding among VAs and is home to one of the larg…
Posted May 21, 2026
Engineering T cells to overcome inhibitory receptor signals that limit the efficacy of adoptive cell therapy against ovarian cancer
US · IL National Institutes of Health · grant
PROJECT SUMMARY Over 20,000 women are diagnosed with ovarian cancer in the United States annually, and over half will die within five years. Outcomes have changed little in the last 20 years, highlighting the need for more effective therap…
Posted May 21, 2026
Chemical Exposure Facility Core
US · IL National Institutes of Health (NIH) · grant
PROJECT SUMMARY - Chemical Exposure Facility Core (CXC) The Chemical Exposure Facility Core (CXC), directed by Kim Anderson, supply passive sampling devices (PSDs) and analytical services to advance environmental health science. Members of …
Posted May 21, 2026
Chemical Mixtures Core
US National Institute of Environmental Health Sciences · grant
SUMMARY – CHEMICAL MIXTURES CORE The mission of the OSU SRC is to identify polycyclic aromatic hydrocarbons (PAHs) in the environment, to characterize their toxicity, to specify the environmental concentrations of those chemicals below whic…
Posted May 21, 2026
Project 3: Defining the biologic role and therapeutic implications of lncRNA in multiple myeloma
US · IL National Institutes of Health (NIH) · grant
Project Summary – Project 3 Dana-Farber Cancer Institute Our longstanding focus has been to understand the multiple myeloma (MM)-bone marrow stromal cell interaction. We have utilized integrated genomic and epigenomic analysis and our in …
Posted May 21, 2026
Defining correlates of protection from dengue illness in a long-term cohort study of multigenerational house-holds in Thailand
US · IL National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID) · grant
PROJECT SUMMARY Dengue viruses (DENV) cause a significant and unchecked burden of human death and disease, with vaccine development hindered by critical gaps in our understanding of how multi-serotypic protection against DENV is generated, …
Posted May 21, 2026
Adaptation of a PrEP Shared-Decision Making Tool for Family Planning Clinics
US National Institute of Mental Health · grant
Women account for ~20% of new HIV infections in the US, and are systematically under-accessed for HIV prevention. The intersection of patient-side barriers (lack of patient knowledge, perceived risk, and medical mistrust), and provider-side…
Posted May 21, 2026
Southwest EDRN Clinical Validation Center for Head and Neck Cancer
US National Cancer Institute · grant
Project Summary/Abstract The goal of the EDRN Southwest Clinical Validation Center for Head and Neck Cancer is to improve oropharyngeal cancer screening through the rigorous validation of salivary biomarkers. The scientific approach of our …
Posted May 21, 2026
Biomarker Developmental Laboratory
US National Cancer Institute · grant
Project Summary/Abstract Cancer screening can detect cancer early and reduce mortality. However, high false positive rates and low sensitivities of lung (LC) and ovarian cancer (OC) screening result in unnecessary surgeries and missed cance…
Posted May 21, 2026
Mechanism and Inhibition of HIV Reverse Transcriptase
US · IL National Institutes of Health (NIH) · grant
PROJECT SUMMARY / ABSTRACT The HIV-1 (Human Immunodeficiency Virus) is a member of the retroviral family which contains a single-stranded RNA genome and is the major etiological agent involved in the development of acquired immunodeficiency…
Posted May 21, 2026
Structure and Function of the VWF Helical Tubule Required for Hemostasis
US National Heart Lung and Blood Institute · grant
PROJECT SUMMARY/ABSTRACT Von Willebrand Disease (VWD), the most common bleeding disorder worldwide, is caused by mutations in von Willebrand Factor (VWF), a large multidomain protein. In the blood, VWF circulates as a long multimer of head-…
Posted May 21, 2026
Identification of optimum spectacle prescriptions for patients with Down syndrome
US National Eye Institute · grant
Project Summary/Abstract: It is known that individuals with Down syndrome (DS) have reduced visual acuity which may result from high levels of refractive error (sphere and cylinder) and elevated levels of higher-order aberrations that are p…
Posted May 21, 2026
Vision Science Training Program
US · OH NIH · grant
Project Summary / Abstract The graduate program in vision science at The Ohio State University has a long track record of training optometrists for careers as clinician scientists. The program has yielded many NIH funded investigators, clin…
Posted May 21, 2026
Short term training: Professional Students in Optometry Schools
US National Eye Institute · grant
Project Summary/Abstract The long-term objective of this program is to expand the number of optometrists trained in research within the profession of optometry to ensure a strong pipeline of individuals available to address the visual and o…
Posted May 21, 2026
EVALUATION AND TESTING SERVICES (ETS) FOR VACCINES AND OTHER BIOLOGICS FOR INFECTIOUS DISEASES
US · IL NIH · grant
The Evaluation and Testing Services (ETS) for Vaccines and Other Biologics for Infectious Diseases contract provides a variety of product development services from early feasibility studies through activities required for the submission of …
Posted May 21, 2026
Defining the Role of Angiotensin II Type 2 Receptor in Bladder Physiology and Pathophysiology with Mouse Models
US National Institute of Diabetes and Digestive and Kidney Diseases · grant
PROJECT SUMMARY The complex communication mechanisms involved in bladder function are not fully understood. Due to this lack of physiological understanding, bladder diseases have remained challenging to treat, resulting in severe detriment …
Posted May 21, 2026
MOSAAIC Cognitive Assessment Reading Center Administrative Supplement
US · IL NIH · grant
Project Summary The Multiethnic Observational Study in American Asian and Pacific Islander Communities (MOSAAIC) is a landmark, NHLBI-funded longitudinal cohort study designed to address critical gaps in health research among Asian American…
Posted May 21, 2026
Multi-ethnic Observational Study in American Asian and Pacific Islander Communities (MOSAAIC): Expanding Recruitment to Adults Aged 65 and Older
US · IL National Institutes of Health (NIH) · grant
Project Summary Older adults of Asian American (AsA), Native Hawaiian, and Pacific Islander (NHPI) backgrounds represent one of the fastest growing demographics in the U.S. However, factors associated with healthy aging in these populations…
Posted May 21, 2026
Hawaiian, Asian American, and Pacific Islander (HAAPI) Coordinating Center
US National Heart Lung and Blood Institute · grant
SUMMARY/ABSTRACT People of Asian, Hawaiian, or Pacific Islander (AsA-NHPI) ancestry, while representing 7.7% of the US population, have been largely underrepresented from NIH-funded prospective epidemiologic studies. As a result, there are …
Posted May 21, 2026
Multi-ethnic Observational Study in American Asian and Pacific Islander Communities (MOSAAIC) Mental Health Administrative Supplement
US · IL NIH · $100-500k · grant
Project Summary The Multiethnic Observational Study in American Asian and Pacific Islander Communities (MOSAAIC) is a groundbreaking study focused on understanding cardiometabolic and mental health disparities in Asian Americans, Native Haw…
Posted May 21, 2026
THE PURPOSE OF THIS MODIFICATION IS TO DE-OBLIGATE NHLBI FUNDING FROM THE WOMEN'S HEALTH INITIATIVE (WHI) - CLINICAL COORDINATING CENTER (CCC).
US · IL NHLBI (National Heart, Lung, and Blood Institute) · grant
The overall goal of the Women’s Health Initiative (WHI) Renewal is to continue to serve as a resource for innovative epidemiological research and to expand knowledge about the determinants of cardiovascular disease among older women, succes…
Posted May 21, 2026
NCI Cancer Screening Research Network: Coordinating and Communication Center
US · IL National Cancer Institute (NCI), National Institutes of Health (NIH) · NAICS 541715 · grant
The promise of early detection to reduce the burden of cancer is an easily understood and highly desired intervention point in the cancer continuum. Recent developments of multicancer detection (MCD) technologies have fueled already strong …
Posted May 21, 2026
Cell-type specific excitability and molecular mechanisms of opioid seeking
US National Institute on Drug Abuse · grant
Project Summary / Abstract Substance use disorders (SUDs) afflict 1 in 10 individuals, and opioid overdose deaths have quintupled over the last 20 years. There is a critical need to develop interventions that can reverse or block opioid-ind…
Posted May 21, 2026
Epigenetic regulation of stress-potentiated ethanol drinking
US · IL NIH · grant
Epigenetic Regulation of Stress-Potentiated Ethanol Drinking PROJECT SUMMARY/ABSTRACT A common mechanism that regulates both stress-sensitivity and alcohol use is epigenetic regulation of gene transcription. Of particular importance in subs…
Posted May 21, 2026